Genomics - Articles

Strategies for Analyzing Bisulfite Sequencing Data

By kassambara, The 15/08/2017 in Bioinformatics

DNA methylation, one of the main epigenetic modifications in the eukaryotic genome, has been shown to play a role in cell-type specific regulation of gene expression, and therefore cell-type... [Read more]

neoantigenR: An R Package for Identifying Tumor Neoantigen from Sequencing Data

By kassambara, The 09/08/2017 in Bioinformatics

This article presents the publication by Shaojun Tang et al., in bioRxiv 2017, entitled:

neoantigenR: An annotation based pipeline for tumor neoantigen identification from sequencing... [Read more]

Identifying Actively Expressed Genes in RNA-seq Gene Expression Studies

By kassambara, The 09/08/2017 in Bioinformatics

This article presents the publication of Hart et al., in BMC Genomics 2017, entitled: "Finding the active genes in deep RNA-seq gene expression studies".

The authors shows that human... [Read more]

Comparison of Computational Tools for Alternatively Spliced Transcript Isoforms Quantification

By kassambara, The 09/08/2017 in Bioinformatics

This article comments the publication, by Zhang et al. in BMC Genomics 2017, entitled:

Evaluation and comparison of computational tools for RNA-seq isoform quantification.

A... [Read more]

Interactive and Reproducible Research for RNA Sequencing Analysis

By kassambara, The 03/08/2017 in R Conference

Next generation sequencing technologies, such as RNA-Seq, generate tens of millions of reads to define the expression levels of the features of interest.

A wide number and variety of... [Read more]